Is This the End for EVAR?

How Neoliberalism Is Shaping the Supply of Unhealthy Commodities and What This Means for NCD Prevention

Alcohol, tobacco, and unhealthy foods contribute greatly to the global burden of non-communicable disease (NCD). Member states of the World Health Organization (WHO) have recognized the critical need to address these three key risk factors through global action plans and policy recommendations. The 2013-2020 WHO action plan identifies the need to engage economic, agricultural and other relevant...

Hepato‐preferential insulins: Is this the end, or the end of the beginning?

Basal insulin peglispro (BIL) is a novel insulin analogue that binds insulin lispro covalently via a urethane bond to a 20-kDa polyethylene glycol molecule (PEG). This analogue, therefore, has a molecular weight of ~25.8 kDa, approximately three times greater than that of native insulin or most insulin analogues. Its hydrodynamic size, however, appears to be even larger, ~90 kDa, similar to a g...

Treatment of alcoholic hepatitis: is this a “dead-end”?

Alcoholic hepatitis (AH) is a clinical syndrome characterized by jaundice and liver failure that develops in subjects with chronic and active alcohol abuse [1]. The shortterm mortality in patients with severe disease, as defined by the Maddrey’s discriminant function, exceeds 30% [2]. Up to now, only two drugs, prednisolone and pentoxifylline, have shown some efficacy for the treatment of this ...

Expanding the Indication for Evar

End-to-end esophagojejunostomy versus standard end-to-side esophagojejunostomy: which one is preferable?

 Abstract Background: End-to-side esophagojejunostomy has almost always been associated with some degree of dysphagia. To overcome this complication we decided to perform an end-to-end anastomosis and compare it with end-to-side Roux-en-Y esophagojejunostomy. Methods: In this prospective study, between 1998 and 2005, 71 patients with a diagnosis of gastric adenocarcinoma underwent total gastrec...